| + |
HNF1A | up-regulates quantity by expression 
transcriptional regulation
|
CDH17 |
0.318 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-253970 |
|
|
Homo sapiens |
HEP-3B Cell, MHCC-97 Cell |
| pmid |
sentence |
| 20568120 |
The present study aims to identify the transcription factors which interact and regulate CDH17 promoter activity that might contribute to the up-regulation of CDH17 gene in human HCC|we identified hepatic nuclear factor 1α (HNF1α) and caudal-related homeobox 2 (CDX2) binding sites at the proximal promoter region which modulate the CDH17 promoter activities in two HCC cell lines (Hep3B and MHCC97L) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CDH17 | up-regulates activity
binding
|
CTNNB1 |
0.693 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265856 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21255999 |
At its C-terminus, cadherin interacts with β-catenin, which dynamically associates with α-catenin, a direct binding partner of filamentous actin |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
calcium(2+) | up-regulates activity
chemical activation
|
CDH17 |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265834 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 22535893 |
Cadherins are Ca(2+)-dependent cell-cell adhesion molecules that play critical roles in animal morphogenesis. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CDX2 | up-regulates quantity by expression
transcriptional regulation
|
CDH17 |
0.416 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-253963 |
|
|
Homo sapiens |
HEP-3B Cell, MHCC-97 Cell |
| pmid |
sentence |
| 20568120 |
The present study aims to identify the transcription factors which interact and regulate CDH17 promoter activity that might contribute to the up-regulation of CDH17 gene in human HCC|we identified hepatic nuclear factor 1α (HNF1α) and caudal-related homeobox 2 (CDX2) binding sites at the proximal promoter region which modulate the CDH17 promoter activities in two HCC cell lines (Hep3B and MHCC97L) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
CDH17
- 
- 