3.0
Summary
| Name |  TRIM26
|
| Full Name | Tripartite motif-containing protein 26 |
| Synonyms | Acid finger protein, AFP, RING finger protein 95, Zinc finger protein 173 | RNF95, ZNF173 |
| Primary ID | Q12899 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors (PRRs). Promotes nuclear IRF3 ubiquitination and proteasomal degradation. Bridges together TBK1 and NEMO during the innate response to viral infection leading to the activation of TBK1. |
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ubiquitination
polyubiquitination