Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-261356 |
|
|
Homo sapiens |
|
pmid |
sentence |
20477988 |
Identification of α1‐antitrypsin as interaction partner of VIP36. The complex formed by VIP36 and alpha1-AT in the Golgi recycled back to the ER. The combined data are most consistent with a function of VIP36 in post-ER quality control of alpha1-AT. We propose that VIP36 acts in post‐ER quality control in the Golgi by binding incompletely folded α1‐AT, which inadvertently escaped ER quality control, and by recycling it back to the ER for an additional round of quality control. |
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