Name	SERPINA1
Full Name	Alpha-1-antitrypsin
Synonyms	Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1 \| AAT, PI
Primary ID	P01009
Links	- -
Type	protein
Relations	4
Function	Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.; FUNCTION