4.0
Summary
| Name |  FOXF2
|
| Full Name | Forkhead box protein F2 |
| Synonyms | Forkhead-related activator 2, FREAC-2, Forkhead-related protein FKHL6, Forkhead-related transcription factor 2 | FKHL6, FREAC2 |
| Primary ID | Q12947 |
| Links |  -  -  |
| Type | protein |
| Relations | 4 |
| Function | Probable transcription activator for a number of lung-specific genes (PubMed:8626802). Mediates up-regulation of the E3 ligase IRF2BPL and drives ubiquitination and degradation of CTNNB1 (PubMed:29374064). |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | FOXF2 | up-regulates quantity by expression 
transcriptional regulation
|
IRF2BPL | 0.253 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | FOXF2 | up-regulates activity
binding
|
TBP | 0.408 |
| Publications: | 1 | Organism: | In Vitro | |
| + | hsa-miR-182-5p | down-regulates quantity by destabilization 
post transcriptional regulation
|
FOXF2 | 0.4 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | GTF2B | up-regulates activity
binding
|
FOXF2 | 0.491 |
| Publications: | 1 | Organism: | Chlorocebus Aethiops | |