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Summary
Name
PTP4A2
Full Name
Protein tyrosine phosphatase type IVA 2
Synonyms
HU-PP-1, OV-1, PTP(CAAXII), Protein-tyrosine phosphatase 4a2, Protein-tyrosine phosphatase of regenerating liver 2, PRL-2 | PRL2, PTPCAAX2
Primary ID
Q12974
Links
-
-
Type
protein
Relations
1
Function
Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Promotes tumors. Inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB.
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by mechanism
none
dephosphorylation
by effect
none
up-regulates
by organism:
none
Homo sapiens
by tissue:
none
by cell-line
none
Relations
Regulator
Mechanism
target
score
ℹ
+
PTP4A2
up-regulates
dephosphorylation
CDK2
0.2
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-119478
Homo sapiens
pmid
sentence
14643450
Cells overexpressing prl-2 exhibited enhanced cyclin-dependent kinase 2 (cdk2) activity
Publications:
1
Organism:
Homo Sapiens