Summary

Name DMP1
Full Name Dentin matrix acidic phosphoprotein 1
Synonyms DMP-1, Dentin matrix protein 1 |
Primary ID Q13316
Links - -
Type protein
Relations 1
Function May have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, unphosphorylated form acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the osteoblast to osteocyte transition phase it is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite. {ECO:0000269|PubMed:12615915}.

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Relations

Regulator Mechanism target score
+ up-regulates quantity img/direct-activation.png phosphorylation DMP1 0.659
Publications: 1 Organism: Homo Sapiens