| + |
FUBP1 | down-regulates quantity by repression 
transcriptional regulation
|
BIK |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-259127 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 19637194 |
FBP1 down-regulates cell cycle inhibitors and proapoptotic genes. Interestingly, we also observed the up-regulation of proapoptotic genes following FBP1 knockdown in Hep3B cells. In particular, elevated expression of the Bcl-2 family members Bik and Noxa was detected. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CD27 | down-regulates quantity by repression
transcriptional regulation
|
BIK |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-93323 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 12324477 |
Bik expression was weakly but significantly down-regulated by cd27 but up-regulated by cd40. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
BIK | down-regulates 
binding
|
BCL2L1 |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-26453 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 7478623 |
We have identified a novel cellular protein, bik, that interacts with the cellular survival-promoting proteins, bcl-2 and bcl-xl in transient transfection assays, bik promotes cell death in a manner similar to the death-promoting members of the bcl-2 family, bax and bak. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CD40 | up-regulates quantity by expression 
transcriptional regulation
|
BIK |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-93390 |
|
|
Homo sapiens |
B-lymphocyte |
| pmid |
sentence |
| 12324477 |
Bik expression was weakly but significantly down-regulated by cd27 but up-regulated by cd40. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
BIK
- 
- 