Name
|
MED21
|
Full Name |
Mediator of RNA polymerase II transcription subunit 21 |
Synonyms |
Mediator complex subunit 21, RNA polymerase II holoenzyme component SRB7, RNAPII complex component SRB7, hSrb7 | SRB7, SURB7 |
Primary ID |
Q13503 |
Links |
- - |
Type |
protein |
Relations |
1 |
Function |
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |