4.0
Summary
| Name |  TRPC3View Modifications |
| Full Name | Short transient receptor potential channel 3 |
| Synonyms | TrpC3, Transient receptor protein 3, TRP-3, hTrp-3, hTrp3 | TRP3 |
| Primary ID | Q13507-3 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol 1,4,5-triphosphate receptors (ITPR) with bound IP3. May also be activated by internal calcium store depletion. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PRKG1 | down-regulates 
phosphorylation
|
TRPC3 (isoform 3) | 0.407 |
| Publications: | 1 | Organism: | Homo Sapiens | |