Summary

Name OLIG2
Full Name Oligodendrocyte transcription factor 2
Synonyms Oligo2, Class B basic helix-loop-helix protein 1, bHLHb1, Class E basic helix-loop-helix protein 19, bHLHe19, Protein kinase C-binding protein 2, Protein kinase C-binding protein RACK17 | BHLHB1, BHLHE19, PRKCBP2, RACK17
Primary ID Q13516
Links - -
Type protein
Relations 2
Function Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Functions together with ZNF488 to promote oligodendrocyte differentiation. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development.

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Relations

Regulator Mechanism target score
+ up-regulates quantity img/indirect-activation.png transcriptional regulation OLIG2 0.362
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png OLIG2 0.31
Publications: 1 Organism: Homo Sapiens