| + |
VEZF1 | up-regulates quantity by expression 
transcriptional regulation
|
EDN1 |
0.281 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266884 |
|
|
Mus musculus |
Heart Endothelial Cell |
| pmid |
sentence |
| 11504723 |
Vascular endothelial zinc finger 1 (Vezf1)/DB1 is a recently identified zinc finger-containing protein that is expressed specifically within endothelial cells during development. In this report, we demonstrate that Vezf1/DB1 is a nuclear localizing protein that potently and specifically activates transcription mediated by the human endothelin-1 promoter, in a Tax-independent manner, in transient transfection assays. Regulation of endothelin-1 promoter activity by Vezf1/DB1 provides a mechanism for endothelin-1 expression in the vascular endothelium during development and to maintain vascular tone |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
VEZF1 | down-regulates quantity by repression 
transcriptional regulation
|
CITED2 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266883 |
|
|
Mus musculus |
Embryonic Stem Cell |
| pmid |
sentence |
| 29794136 |
The transcription factor Vezf1 represses the expression of the antiangiogenic factor Cited2 in endothelial cells |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
3.0
VEZF1
- 
- 