Summary

Name CRMP1
Full Name Dihydropyrimidinase-related protein 1
Synonyms DRP-1, Collapsin response mediator protein 1, CRMP-1, Unc-33-like phosphoprotein 3, ULIP-3 | DPYSL1, ULIP3
Primary ID Q14194
Links - -
Type protein
Relations 6
Function Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton (PubMed:25358863). Plays a role in axon guidance (PubMed:25358863). During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone (PubMed:25358863). Involved in invasive growth and cell migration (PubMed:11562390). May participate in cytokinesis (PubMed:19799413).

Viewer

Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png phosphorylation CRMP1 0.442
Publications: 3 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation CRMP1 0.608
Publications: 3 Organism: Homo Sapiens