Summary

Name SELPLG
Full Name P-selectin glycoprotein ligand 1
Synonyms PSGL-1, Selectin P ligand
Primary ID Q14242
Links - -
Type protein
Relations 3
Pathways Neutrophils: Adhesion and migration
Function A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture.

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding SELE 0.763
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding SELP 0.925
Publications: 2 Organism: Homo Sapiens
Tissue: Ovary