Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-265162 |
|
|
Homo sapiens |
|
pmid |
sentence |
31848472 |
The processed SREBP2, designated nuclear SREBP2 (nSREBP2), then enters the nucleus as a homodimer, binds to the sterol regulatory element (SRE) sequence in the promoters of target genes, including HMGCR and SQLE (encoding squalene monooxygenase), and upregulates their transcription |
|