Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-253951 |
|
|
Homo sapiens |
Pancreatic Cancer Cell |
pmid |
sentence |
17312387 |
In contrast, BTF3 silencing resulted in down-regulation of several cancer-associated genes, including EPHB2, ABL2, HPSE2 and ATM, and up-regulation of KRAG, RRAS2, NFkappa-B, MRVI1, MADCAM1 and others. In conclusion, BTF3 is overexpressed in PDAC, where it acts as a transcriptional regulator rather than a direct modulator of apoptosis. |
|