+ |
Caspase 3 complex | down-regulates activity
cleavage
|
GOLGB1 |
0.256 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-261235 |
Asp1881 |
LSQISTKdGELKMLQ |
Homo sapiens |
|
pmid |
sentence |
14970262 |
Giantin and syntaxin 5 are cleaved by caspase-3. Given that both giantin and syntaxin 5 are cleaved at an early stage during apoptosis, we anticipated that, at the very least, the delivery of ER-derived transport intermediates to the Golgi would be impaired in apoptotic cells. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
GOLGB1 | up-regulates activity
binding
|
GOLGA2 |
0.761 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-261238 |
|
|
Homo sapiens |
|
pmid |
sentence |
23555793 |
The “cis-golgin tether” is one of the most well-characterized golgin tether complexes. It is composed of the COPI vesicle-associated golgin giantin linked to Golgi membrane-associated GM130 via p115. GM130 is in turn linked to GRASP65 via a PDZ-like domain. GRASP65 is anchored to the Golgi membrane through N-terminal myristoylation as well as through binding to other Golgi proteins [10]. Together, these proteins appear to mediate vesicle tethering at the cis-Golgi membrane. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
USO1 | up-regulates activity
binding
|
GOLGB1 |
0.834 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-261237 |
|
|
Homo sapiens |
|
pmid |
sentence |
23555793 |
The “cis-golgin tether” is one of the most well-characterized golgin tether complexes. It is composed of the COPI vesicle-associated golgin giantin linked to Golgi membrane-associated GM130 via p115. GM130 is in turn linked to GRASP65 via a PDZ-like domain. GRASP65 is anchored to the Golgi membrane through N-terminal myristoylation as well as through binding to other Golgi proteins [10]. Together, these proteins appear to mediate vesicle tethering at the cis-Golgi membrane. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |