140 kDa nucleolar phosphoprotein, Nopp140, Hepatitis C virus NS5A-transactivated protein 13, HCV NS5A-transactivated protein 13, Nucleolar 130 kDa protein, Nucleolar phosphoprotein p130 | KIAA0035, NS5ATP13
Primary ID
Q14978
Links
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Type
protein
Relations
3
Function
Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification (PubMed:10567578, PubMed:26399832). Required for neural crest specification
Here we demonstrate that protein kinase a (pka)-dependent phosphorylation of nopp140 at ser 627, together with c/ebpbeta, induces agp gene expression synergistically.