Summary

Name IQCB1
Full Name IQ calmodulin-binding motif-containing protein 1
Synonyms Nephrocystin-5, p53 and DNA damage-regulated IQ motif protein, PIQ | KIAA0036, NPHP5
Primary ID Q15051
Links - -
Type protein
Relations 1
Function Involved in ciliogenesis. The function in an early step in cilia formation depends on its association with CEP290/NPHP6 (PubMed:21565611, PubMed:23446637). Involved in regulation of the BBSome complex integrity, specifically for presence of BBS2 and BBS5 in the complex, and in ciliary targeting of selected BBSome cargos. May play a role in controlling entry of the BBSome complex to cilia possibly implicating CEP290/NPHP6 (PubMed:25552655).

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates quantity by destabilization img/direct_inhibition.png ubiquitination IQCB1 0.2
Publications: 1 Organism: Homo Sapiens