3.0
Summary
| Name |  MARCHF7
|
| Full Name | E3 ubiquitin-protein ligase MARCHF7 |
| Synonyms | Axotrophin, Membrane-associated RING finger protein 7, Membrane-associated RING-CH protein VII, MARCH-VII, RING finger protein 177, RING-type E3 ubiquitin transferase MARCH7 | AXOT, RNF177 |
| Primary ID | Q9H992 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | E3 ubiquitin-protein ligase which may specifically enhance the E2 activity of HIP2. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates (PubMed:16868077). May be involved in T-cell proliferation by regulating LIF secretion (By similarity). May play a role in lysosome homeostasis (PubMed:31270356). |
ubiquitination