Summary

Name NOMO1
Full Name BOS complex subunit NOMO1
Synonyms Nodal modulator 1, pM5 protein | PM5
Primary ID Q15155
Links - -
Type protein
Relations 1
Function Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes (PubMed:32820719, PubMed:36261522). The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions (PubMed:36261522).

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Relations

Regulator Mechanism target score ℹ
+ NOMO1form complex img/form-complex.png binding BOS complex, NOMO1 variant 0.468
Publications: 1 Organism: Homo Sapiens