Name
|
TTF1
|
Full Name |
Transcription termination factor 1 |
Synonyms |
TTF-1, RNA polymerase I termination factor, Transcription termination factor I, TTF-I |
Primary ID |
Q15361 |
Links |
- - |
Type |
protein |
Relations |
1 |
Function |
Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity. |