Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-262625 |
Ser43 |
VKRIREEsGARINIS |
Mus musculus |
NMuMg Cell |
pmid |
sentence |
20154680 |
We show that heterogeneous nuclear ribonucleoprotein E1 (hnRNP E1) binds a structural, 33-nucleotide TGF-beta-activated translation (BAT) element in the 3' untranslated region of disabled-2 (Dab2) and interleukin-like EMT inducer (ILEI) transcripts, and represses their translation.TGF-beta activation leads to phosphorylation at Ser 43 of hnRNP E1 by protein kinase Bbeta/Akt2, inducing its release from the BAT element and translational activation of Dab2 and ILEI messenger RNAs. |
|