Summary

Name FCN2
Full Name Ficolin-2
Synonyms 37 kDa elastin-binding protein, Collagen/fibrinogen domain-containing protein 2, EBP-37, Ficolin-B, Ficolin-beta, Hucolin, L-ficolin, Serum lectin p35 | FCNL
Primary ID Q15485
Links - -
Type protein
Relations 3
Function May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding MASP1 0.781
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding FCN2 0.7
Publications: 1 Organism: In Vitro
+ up-regulates activity img/direct-activation.png binding MASP2 0.628
Publications: 1