| Name
|
 MED22
|
| Full Name |
Mediator of RNA polymerase II transcription subunit 22 |
| Synonyms |
Mediator complex subunit 22, Surfeit locus protein 5, Surf-5 | SURF5 |
| Primary ID |
Q15528 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
1 |
| Function |
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
3.0
binding