| + |
TRIP11 | up-regulates 
binding
|
THRA |
0.395 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-50348 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 9256431 |
Trip230 binds to rb independently of thyroid hormone while it forms a complex with tr in a thyroid hormone-dependent manner. Ectopic expression of the protein trip230 in cells, but not a mutant form that does not bind to tr, enhances specifically tr-dependent transcriptional activity. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RB1 | down-regulates 
binding
|
TRIP11 |
0.329 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-50266 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 9256431 |
The wild-type rb is able to interact with the rb-binding domain of trip230 / rb represses trip230-mediated activation of tr-regulated transcription. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TRIP11 | up-regulates
binding
|
THRB |
0.321 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-50421 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 9256431 |
Trip230 binds to rb independently of thyroid hormone while it forms a complex with tr in a thyroid hormone-dependent manner. Ectopic expression of the protein trip230 in cells, but not a mutant form that does not bind to tr, enhances specifically tr-dependent transcriptional activity. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TRIP11 | up-regulates
binding
|
THR |
0.432 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270295 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 9256431 |
Trip230 binds to rb independently of thyroid hormone while it forms a complex with tr in a thyroid hormone-dependent manner. Ectopic expression of the protein trip230 in cells, but not a mutant form that does not bind to tr, enhances specifically tr-dependent transcriptional activity. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269879 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 9256431 |
Trip230 binds to rb independently of thyroid hormone while it forms a complex with tr in a thyroid hormone-dependent manner. Ectopic expression of the protein trip230 in cells, but not a mutant form that does not bind to tr, enhances specifically tr-dependent transcriptional activity. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
TRIP11 | up-regulates activity
binding
|
THR |
0.432 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267803 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 9256431 |
Trip230 binds to rb independently of thyroid hormone while it forms a complex with tr in a thyroid hormone-dependent manner. Ectopic expression of the protein trip230 in cells, but not a mutant form that does not bind to tr, enhances specifically tr-dependent transcriptional activity. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RAB2A | up-regulates activity
binding
|
TRIP11 |
0.405 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-261300 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 25473115 |
Vesicle-associated Rab2 then mediates attachment to the Rab2 binding site within the central coiled-coil region of GMAP-210, bringing the vesicle into closer proximity to the target membrane. GMAP-210 function in vivo is dependent upon its ability to tether membranes, which is mediated exclusively by the amino-terminal ALPS motif. Binding to Rab2 is also important for GMAP-210 function, although it is dispensable for tethering per se. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
TRIP11
- 
- 