3.0
Summary
| Name |  ZRSR2
|
| Full Name | U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 |
| Synonyms | CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2, Renal carcinoma antigen NY-REN-20, U2(RNU2) small nuclear RNA auxiliary factor 1-like 2, U2AF35-related protein, URP | U2AF1-RS2, U2AF1L2, U2AF1RS2, URP |
| Primary ID | Q15696 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Pre-mRNA-binding protein required for splicing of both U2- and U12-type introns. Selectively interacts with the 3'-splice site of U2- and U12-type pre-mRNAs and promotes different steps in U2 and U12 intron splicing. Recruited to U12 pre-mRNAs in an ATP-dependent manner and is required for assembly of the prespliceosome, a precursor to other spliceosomal complexes. For U2-type introns, it is selectively and specifically required for the second step of splicing. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | ZRSR2 | form complex 
binding
|
ZRSR2/U2AF2 | 0.771 |
| Publications: | 1 | Organism: | Homo Sapiens | |