Relation Results

Summary

Name ZRSR2/U2AF2
Primary ID SIGNOR-C81
Type complex
Formed by U2AF2, ZRSR2
Relations 3

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Type: Score: Layout: SPV 
0.7670.7670.7U2AF2ZRSR2/U2AF2ZRSR2Spliceosomal_snRNP_assembly

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Relations
Regulator
Mechanism
target
score ℹ
+ U2AF2form complex img/form-complex.png binding ZRSR2/U2AF2 0.767
Identifier Residue Sequence Organism Cell Line
SIGNOR-50173 Homo sapiens
pmid sentence
Recognition of a functional 3' splice site in pre-mrna splicing requires a heterodimer of the proteins u2af65/u2af35.
Publications: 1 Organism: Homo Sapiens
+ ZRSR2form complex img/form-complex.png binding ZRSR2/U2AF2 0.767
Identifier Residue Sequence Organism Cell Line
SIGNOR-50176 Homo sapiens
pmid sentence
Recognition of a functional 3' splice site in pre-mrna splicing requires a heterodimer of the proteins u2af65/u2af35.
Publications: 1 Organism: Homo Sapiens
+ ZRSR2/U2AF2up-regulates img/indirect-activation.png Spliceosomal_snRNP_assembly 0.7
Identifier Residue Sequence Organism Cell Line
SIGNOR-263946 Homo sapiens
pmid sentence
The essential splicing factor U2AF (U2 auxiliary factor) is a heterodimer composed of 65-kDa (U2AF(65)) and 35-kDa (U2AF(35)) subunits. U2AF(35) has multiple functions in pre-mRNA splicing. First, U2AF(35) has been shown to function by directly interacting with the AG at the 3' splice site. Second, U2AF(35) is thought to play a role in the recruitment of U2AF(65) by serine-arginine-rich (SR) proteins in enhancer-dependent splicing.
Publications: 1 Organism: Homo Sapiens
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