3.0
Summary
| Name |  CD226
|
| Full Name | CD226 antigen |
| Synonyms | DNAX accessory molecule 1, DNAM-1 | DNAM1 |
| Primary ID | Q15762 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell (PubMed:8673704). Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding (PubMed:26755705). |
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