3.0
Summary
| Name |  NECTIN2View Modifications |
| Full Name | Nectin-2 |
| Synonyms | Herpes virus entry mediator B, Herpesvirus entry mediator B, HveB, Nectin cell adhesion molecule 2, Poliovirus receptor-related protein 2 | HVEB, PRR2, PVRL2 |
| Primary ID | Q92692 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive (PubMed:26755705). Probable cell adhesion protein (PubMed:9657005). |
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