3.0
Summary
| Name |  H2BC21View Modifications |
| Full Name | Histone H2B type 2-E |
| Synonyms | H2B-clustered histone 21, Histone H2B-GL105, Histone H2B.q, H2B/q | H2BFQ, HIST2H2BE |
| Primary ID | Q16778 |
| Links |  -  -  |
| Type | protein |
| Relations | 4 |
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.; FUNCTION |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | MSL2 | down-regulates activity 
monoubiquitination
|
H2BC21 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | MSL1 | down-regulates activity
monoubiquitination
|
H2BC21 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | IRX1 | down-regulates quantity by repression 
transcriptional regulation
|
H2BC21 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | SLBP | up-regulates quantity by expression 
translation regulation
|
H2BC21 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |