| + |
TYSND1 | down-regulates activity 
cleavage
|
TYSND1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-261053 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 22002062 |
Self-cleavage of Tysnd1 in the active oligomer most likely inactivates its protease activity. Subsequently, the cleaved products are degraded by PsLon and removed from the Tysnd1 oligomer. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TYSND1 | up-regulates activity 
cleavage
|
ACOX1 |
0.683 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-261057 |
|
|
in vitro |
|
| pmid |
sentence |
| 17255948 |
Here, we demonstrate that Tysnd1, a previously uncharacterized protein, is responsible both for the removal of the leader peptide from PTS2 proteins and for the specific processing of PTS1 proteins. All of the identified Tysnd1 substrates catalyze peroxisomal β-oxidation. In vitro cleavage of Acox1, Scp2 and prethiolase by recombinant Tysnd1. |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
LONP2 | down-regulates quantity by destabilization
cleavage
|
TYSND1 |
0.646 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-261054 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 22002062 |
Self-cleavage of Tysnd1 in the active oligomer most likely inactivates its protease activity. Subsequently, the cleaved products are degraded by PsLon and removed from the Tysnd1 oligomer. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TYSND1 | up-regulates activity
cleavage
|
SCP2 |
0.476 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-261055 |
|
|
in vitro |
|
| pmid |
sentence |
| 17255948 |
Here, we demonstrate that Tysnd1, a previously uncharacterized protein, is responsible both for the removal of the leader peptide from PTS2 proteins and for the specific processing of PTS1 proteins. All of the identified Tysnd1 substrates catalyze peroxisomal β-oxidation. In vitro cleavage of Acox1, Scp2 and prethiolase by recombinant Tysnd1. |
|
| Publications: |
1 |
Organism: |
In Vitro |
3.0
TYSND1
- 
- 