Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-264567 |
Ser181 |
YQPRRRKsVKNGQAE |
|
|
pmid |
sentence |
32277958 |
Here we investigated the mechanism of ADCK5 involved in regulating invasion and migration of lung cancer cells, and showed that ADCK5 might regulate the expression of tumor oncogene human pituitary tumor transforming gene-1 (PTTG1) by phosphorylating transcription factor SOX9|Mutagenesis of potential serine phosphorylation sites on SOX9 indicated that serine 181 might be required to maintain transcription activation of SOX9 as well as increase PTTG1 levels. |
|