3.0
Summary
| Name |  TIGIT
|
| Full Name | T-cell immunoreceptor with Ig and ITIM domains |
| Synonyms | V-set and immunoglobulin domain-containing protein 9, V-set and transmembrane domain-containing protein 3 | VSIG9, VSTM3 |
| Primary ID | Q495A1 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. |
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