Summary

Name CDCA8
Full Name Borealin
Synonyms Cell division cycle-associated protein 8, Dasra-B, hDasra-B, Pluripotent embryonic stem cell-related gene 3 protein | PESCRG3
Primary ID Q53HL2
Links - -
Type protein
Relations 6
Function Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png phosphorylation CDCA8 0.475
Publications: 5 Organism: Homo Sapiens
+ form complex img/form-complex.png binding CPC 0.85
Publications: 1 Organism: Homo Sapiens