| + |
H3C1 | up-regulates quantity 
binding
|
CPC |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-275422 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 24413556 |
Histone modifications coordinate the chromatin localization of key regulatory factors in mitosis. For example, mitotic phosphorylation of Histone H3 threonine-3 (H3T3ph) by Haspin creates a binding site for the chromosomal passenger complex (CPC). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CDCA8 | form complex 
binding
|
CPC |
0.85 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-275423 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 23175282 |
It is now known that the chromosomal passenger complex (CPC) is composed of four subunits: the enzymatic component Aurora B and the three regulatory and targeting components INCENP, Survivin and Borealin (also known as Dasra)5–7 (Figure 1A). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
BIRC5 | form complex
binding
|
CPC |
0.791 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-275424 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 23175282 |
It is now known that the chromosomal passenger complex (CPC) is composed of four subunits: the enzymatic component Aurora B and the three regulatory and targeting components INCENP, Survivin and Borealin (also known as Dasra)5–7 (Figure 1A). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CPC | up-regulates 
|
Chromosome_segregation |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-275427 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 37292983 |
Here, we focus on the chromosome passenger complex (CPC), that forms a chromatin body that regulates chromosome segregation in mitosis. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
INCENP | form complex
binding
|
CPC |
0.873 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-275425 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 23175282 |
It is now known that the chromosomal passenger complex (CPC) is composed of four subunits: the enzymatic component Aurora B and the three regulatory and targeting components INCENP, Survivin and Borealin (also known as Dasra)5–7 (Figure 1A). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
AURKB | form complex
binding
|
CPC |
0.858 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-275426 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 23175282 |
It is now known that the chromosomal passenger complex (CPC) is composed of four subunits: the enzymatic component Aurora B and the three regulatory and targeting components INCENP, Survivin and Borealin (also known as Dasra)5–7 (Figure 1A). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
CPC
CPX-116