Summary

Name ODF2
Full Name Outer dense fiber protein 2
Synonyms Cenexin, Outer dense fiber of sperm tails protein 2 |
Primary ID Q5BJF6
Links - -
Type protein
Relations 2
Function Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly. {ECO:0000269|PubMed:16966375}.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation ODF2 0.524
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png ubiquitination ODF2 0.2
Publications: 1 Organism: In Vitro