Summary

Name HERC4
Full Name Probable E3 ubiquitin-protein ligase HERC4
Synonyms HECT domain and RCC1-like domain-containing protein 4, HECT-type E3 ubiquitin transferase HERC4 | KIAA1593
Primary ID Q5GLZ8
Links - -
Type protein
Relations 1
Function Probable E3 ubiquitin-protein ligase involved in either protein trafficking or in the distribution of cellular structures. Required for spermatozoon maturation and fertility, and for the removal of the cytoplasmic droplet of the spermatozoon. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer it to targeted substrates.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png ubiquitination HERC4 0.2
Publications: 1 Organism: Homo Sapiens