Summary

Name INTS11
Full Name Integrator complex subunit 11
Synonyms Int11, Cleavage and polyadenylation-specific factor 3-like protein, CPSF3-like protein, Protein related to CPSF subunits of 68 kDa, RC-68 | INTS11, RC68
Primary ID Q5TA45
Links - -
Type protein
Relations 1
Function Catalytic component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates the snRNAs 3' cleavage. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267).

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding Integrator complex 0.2
Publications: 1 Organism: Drosophila Melanogaster