3.0
Summary
| Name |  RNF220
|
| Full Name | E3 ubiquitin-protein ligase RNF220 |
| Synonyms | RING finger protein 220, RING-type E3 ubiquitin transferase RNF220 | C1orf164 |
| Primary ID | Q5VTB9 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity). Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling (PubMed:25266658, PubMed:33964137). Plays a critical role in the regulation of nuclear lamina (PubMed:33964137). |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
ubiquitination
polyubiquitination