3.0
Summary
| Name |  INTS3
|
| Full Name | Integrator complex subunit 3 |
| Synonyms | Int3, SOSS complex subunit A, Sensor of single-strand DNA complex subunit A, SOSS-A, Sensor of ssDNA subunit A | C1orf193, C1orf60 |
| Primary ID | Q68E01 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Component of the Integrator (INT) complex. The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267). |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | INTS3 | form complex 
binding
|
Integrator complex | 0.89 |
| Publications: | 1 | Organism: | Drosophila Melanogaster | |