Summary

Name PPP4R3A
Full Name Serine/threonine-protein phosphatase 4 regulatory subunit 3A
Synonyms SMEK homolog 1 | KIAA2010, PP4R3A, SMEK1
Primary ID Q6IN85
Links - -
Type protein
Relations 1
Function Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphorylated on 'Ser-140' (gamma-H2AX) generated during DNA replication and required for DNA DSB repair.

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding PPP4C 0.2
Publications: 1 Organism: Homo Sapiens