Summary

Name PLEKHA7
Full Name Pleckstrin homology domain-containing family A member 7
Synonyms PH domain-containing family A member 7 |
Primary ID Q6IQ23
Links - -
Type protein
Relations 2
Function Required for zonula adherens biogenesis and maintenance (PubMed:19041755). Acts via its interaction with CAMSAP3, which anchors microtubules at their minus-ends to zonula adherens, leading to the recruitment of KIFC3 kinesin to the junctional site (PubMed:19041755). Mediates docking of ADAM10 to zonula adherens through a PDZD11-dependent interaction with the ADAM10-binding protein TSPAN33 (PubMed:30463011).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding PDZD11 0.39
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates activity img/direct-activation.png binding TSPAN33 0.409
Publications: 1 Organism: Rattus Norvegicus