+ |
TTBK2 | down-regulates activity
phosphorylation
|
KIF2A |
0.406 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-260926 |
Ser135 |
SSAQQNGsVSDISPV |
Chlorocebus aethiops |
|
pmid |
sentence |
26323690 |
TTBK2 phosphorylates KIF2A primarily at growing MT ends and counteracts the depolymerization activity of KIF2A |
|
Publications: |
1 |
Organism: |
Chlorocebus Aethiops |
+ |
TTBK2 | down-regulates quantity
phosphorylation
|
MPHOSPH9 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-278998 |
|
|
Homo sapiens |
|
pmid |
sentence |
30375385 |
Additionally, in vivo ubiquitin assays showed that expression of either the kinase-dead TTBK2 or the MPP9-S629 and S636-2A mutant significantly decreased the ubiquitination level of MPP9.|Also, the S629A mutant almost abolished the phosphorylation of MPP9 by TTBK2 in the kinase assay in vitro, suggesting that S629 is the main site for MPP9 phosphorylation by TTBK2. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |