3.0
The
SIG
naling
N
etwork
O
pen
R
esource
HOME
ABOUT
DOCUMENTATION
USER GUIDE
STATISTICS
DOWNLOADS
APIs
CONTACT
LOGIN
Summary
Name
TTBK2
View Modifications
Full Name
Tau-tubulin kinase 2
Synonyms
TTBK2_HUMAN | KIAA0847
Primary ID
Q6IQ55
Links
-
-
Type
protein
Relations
1
Function
Serine/threonine kinase that acts as a key regulator of ciliogenesis
Viewer
Search Tools
Refine search:
by mechanism
none
phosphorylation
by effect
none
down-regulates activity
by organism:
none
Chlorocebus aethiops
by tissue:
none
by cell-line
none
▶
Modifications Tables
TTBK2 as Modifier
Residue
Sequence
Target
Effect
Modification
Ser135
SSAQQNGsVSDISPV
KIF2A
inhibition
phosphorylation
Relations
Regulator
Mechanism
target
score
ℹ
+
TTBK2
down-regulates activity
phosphorylation
KIF2A
0.417
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-260926
Ser135
SSAQQNGsVSDISPV
Chlorocebus aethiops
pmid
sentence
26323690
TTBK2 phosphorylates KIF2A primarily at growing MT ends and counteracts the depolymerization activity of KIF2A
Publications:
1
Organism:
Chlorocebus Aethiops