Summary

Name KIF2A
Full Name Kinesin-like protein KIF2A
Synonyms Kinesin-2, hK2 | KIF2, KNS2
Primary ID O00139
Links - -
Type protein
Relations 3
Function Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity.

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png phosphorylation KIF2A 0.417
Publications: 1 Organism: Chlorocebus Aethiops
+ up-regulates activity img/direct-activation.png binding KIF2A 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png Minus-end directed microtubule movement 0.7
Publications: 1 Organism: Homo Sapiens