+ |
TTBK2 | down-regulates activity
phosphorylation
|
KIF2A |
0.417 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-260926 |
Ser135 |
SSAQQNGsVSDISPV |
Chlorocebus aethiops |
|
pmid |
sentence |
26323690 |
TTBK2 phosphorylates KIF2A primarily at growing MT ends and counteracts the depolymerization activity of KIF2A |
|
Publications: |
1 |
Organism: |
Chlorocebus Aethiops |
+ |
WDCP | up-regulates activity
binding
|
KIF2A |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-273732 |
|
|
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
30297404 |
PLK1 Phosphorylates MMAP to Promote Its Interaction with KIF2A and MRE11. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
KIF2A | up-regulates
|
Minus-end directed microtubule movement |
0.7 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-272533 |
|
|
Homo sapiens |
|
pmid |
sentence |
19773780 |
In general, N-kinesins and C-kinesins drive microtubule plus end- and minus end-directed motilities, respectively, and M-kinesins depolymerize microtubules1,9 (Box 1).|Forty-five genes that encode kinesin superfamily proteins (also known as KIFs) have been discovered in the mouse and human genomes.|KIFs are molecular motors that directionally transport various cargos, including membranous organelles, protein complexes and mRNAs, along the microtubule system. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |