4.0
Summary
| Name |  KIF2AView Modifications |
| Full Name | Kinesin-like protein KIF2A |
| Synonyms | Kinesin-2, hK2 | KIF2, KNS2 |
| Primary ID | O00139 |
| Links |  -  -  |
| Type | protein |
| Relations | 4 |
| Function | Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | TTBK2 | down-regulates activity 
phosphorylation
|
KIF2A | 0.407 |
| Publications: | 1 | Organism: | Chlorocebus Aethiops | |
| + | PLK1 | up-regulates activity 
phosphorylation
|
KIF2A | 0.687 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | KIF2A | up-regulates 
|
Minus-end directed microtubule movement | 0.7 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | WDCP | up-regulates activity
binding
|
KIF2A | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |