| + |
MAST2 | down-regulates activity
phosphorylation
|
SLC9A3 |
0.457 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-279229 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 16159897 |
Coexpression of MAST205 inhibits the activity of Na +/H+ exchanger NHE3.|Consistent with these results, we found that MAST205 phosphorylated NHE3 under in vitro conditions. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MAST2 | up-regulates
phosphorylation
|
PTEN |
0.666 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-138051 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15951562 |
We further demonstrate that binding of pten to specific pdz domains diminishes its degradation rate and facilitates its phosphorylation by mast kinases. Our results suggest a regulatory role of pdz domain binding on pten function by controlling its stability and phosphorylation status. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |