| + |
SP3 | up-regulates quantity by expression 
transcriptional regulation
|
SLC9A3 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254271 |
|
|
Drosophila melanogaster |
SCHNEIDER-2 Cell |
| pmid |
sentence |
| 16464174 |
Co-transfection of Sp1 or Sp3 into SL2 cells activated the NHE3-reporter constructs, suggesting that Sp1 and Sp3 act as positive regulators of the NHE3 expression. In addition, overexpression of EGR-1 was sufficient to transactivate the NHE3-reporter gene activity |
|
| Publications: |
1 |
Organism: |
Drosophila Melanogaster |
| + |
SP1 | up-regulates quantity by expression
transcriptional regulation
|
SLC9A3 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254270 |
|
|
Drosophila melanogaster |
SCHNEIDER-2 Cell |
| pmid |
sentence |
| 16464174 |
Co-transfection of Sp1 or Sp3 into SL2 cells activated the NHE3-reporter constructs, suggesting that Sp1 and Sp3 act as positive regulators of the NHE3 expression. In addition, overexpression of EGR-1 was sufficient to transactivate the NHE3-reporter gene activity |
|
| Publications: |
1 |
Organism: |
Drosophila Melanogaster |
| + |
EGR1 | up-regulates quantity by expression
transcriptional regulation
|
SLC9A3 |
0.248 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254269 |
|
|
Drosophila melanogaster |
SCHNEIDER-2 Cell |
| pmid |
sentence |
| 16464174 |
Transcriptional stimulation of the human NHE3 promoter activity by PMA: PKC independence and involvement of the transcription factor EGR-1|Co-transfection of Sp1 or Sp3 into SL2 cells activated the NHE3-reporter constructs, suggesting that Sp1 and Sp3 act as positive regulators of the NHE3 expression. In addition, overexpression of EGR-1 was sufficient to transactivate the NHE3-reporter gene activity |
|
| Publications: |
1 |
Organism: |
Drosophila Melanogaster |
| + |
SLC9A3 | up-regulates quantity 
relocalization
|
sodium(1+) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265602 |
|
|
Homo sapiens |
Neuron |
| pmid |
sentence |
| 31507243 |
Na+/H+ exchangers play pivotal roles in the control of cell and tissue pH by mediating the electroneutral exchange of Na+ and H+ across cellular membranes. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SLC9A3 | down-regulates quantity 
relocalization
|
hydron |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265593 |
|
|
Homo sapiens |
Neuron |
| pmid |
sentence |
| 31507243 |
Na+/H+ exchangers play pivotal roles in the control of cell and tissue pH by mediating the electroneutral exchange of Na+ and H+ across cellular membranes. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
SLC9A3
- 
- 