3.0
Summary
| Name |  SLC27A1
|
| Full Name | Long-chain fatty acid transport protein 1 |
| Synonyms | FATP-1, Fatty acid transport protein 1, Solute carrier family 27 member 1 | ACSVL5, FATP1 |
| Primary ID | Q6PCB7 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Mediates the ATP-dependent import of long-chain fatty acids (LCFA) into the cell by mediating their translocation at the plasma membrane (PubMed:28178239). Has also an acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism (By similarity). Probably involved in fatty acid transport across the blood barrier (PubMed:21395585). |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | SLC27A1 | up-regulates quantity 
relocalization
|
Fatty acid | 0.7 |
| Publications: | 1 | Organism: | Homo Sapiens | |