+ |
DLK2 | down-regulates
binding
|
NOTCH1 |
0.294 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-172864 |
|
|
Homo sapiens |
|
pmid |
sentence |
21419176 |
In this work, we demonstrate, for the first time, that dlk2 interacts with itself, with dlk1, and with the same notch1 receptor region as dlk1 does. We demonstrate also that the interaction of dlk2 with notch1 similarly results in an notch signaling in preadipocytes and mouse embryo fibloblasts. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
DLK2 | down-regulates activity
binding
|
NOTCH1 |
0.294 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-219377 |
|
|
Mus musculus |
|
pmid |
sentence |
21419176 |
Moreover, the interaction of DLK1 with NOTCH1 caused an inhibition of basal NOTCH signaling in preadipocytes and mesenchymal multipotent cells. In this work, we demonstrate, for the first time, that DLK2 interacts with itself, with DLK1, and with the same NOTCH1 receptor region as DLK1 does. We demonstrate also that the interaction of DLK2 with NOTCH1 similarly results in an inhibition of NOTCH signaling in preadipocytes and Mouse Embryo fibloblasts. |
|
Publications: |
1 |
Organism: |
Mus Musculus |
Tissue: |
MEF Cell |